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Discovery of small molecule positive allosteric modulators of the secretin receptor
The secretin receptor (SCTR) is a prototypic Class B1 G protein-coupled receptor (GPCR) that represents a key target for the development of therapeutics for the treatment of cardiovascular, gastrointestinal, and metabolic disorders. However, no non-peptidic molecules targeting this receptor have yet...
Shranjeno v:
| izdano v: | Biochem Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8146373/ https://ncbi.nlm.nih.gov/pubmed/33545115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2021.114451 |
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