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Fluorescence Polarization Screening for Allosteric Small Molecule Ligands of the Cholecystokinin Receptor

The success in screening for drug candidates is highly dependent on the power of the strategy implemented. In this work, we report and characterize a novel fluorescent benzodiazepine antagonist of the type 1 cholecystokinin receptor (3-(3-(7-fluoro-1-(2-isopropyl(4-methoxyphenyl)amino)-2-oxoethyl)-2...

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Detalhes bibliográficos
Main Authors: Harikumar, Kaleeckal G., Cawston, Erin E., Miller, Laurence J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3148107/
https://ncbi.nlm.nih.gov/pubmed/21395402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2010.0310
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