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Ligand-induced internalization of the type 1 cholecystokinin receptor independent of recognized signaling activity

Receptor ligands, identified as antagonists, based on the absence of stimulation of signaling, can rarely stimulate receptor internalization. d-Tyr-Gly-[(Nle(28,31),d-Trp(30))CCK-26–32]-2-phenylethyl ester (d-Trp-OPE) is such a ligand that binds to the cholecystokinin (CCK) receptor and stimulates i...

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Autores principales: Cawston, Erin E., Harikumar, Kaleeckal G., Miller, Laurence J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287154/
https://ncbi.nlm.nih.gov/pubmed/22049215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00193.2011
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