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Chromosome-Specific and Global Effects of Aneuploidy in Saccharomyces cerevisiae

Aneuploidy, an unbalanced karyotype in which one or more chromosomes are present in excess or reduced copy number, causes an array of known phenotypes including proteotoxicity, genomic instability, and slowed proliferation. However, the molecular consequences of aneuploidy are poorly understood and...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Dodgson, Stacie E., Kim, Sharon, Costanzo, Michael, Baryshnikova, Anastasia, Morse, Darcy L., Kaiser, Chris A., Boone, Charles, Amon, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905547/
https://ncbi.nlm.nih.gov/pubmed/26837754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.185660
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