Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells

Acinar-to-ductal metaplasia (ADM) occurring in cerulein-mediated pancreatitis or in oncogenic Kras-driven pancreatic cancer development is accompanied by extensive changes in the transcriptional program. In this process, acinar cells shut down the expression of acinar specific differentiation genes...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Benitz, Simone, Regel, Ivonne, Reinhard, Tobias, Popp, Anna, Schäffer, Isabell, Raulefs, Susanne, Kong, Bo, Esposito, Irene, Michalski, Christoph W., Kleeff, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905483/
https://ncbi.nlm.nih.gov/pubmed/26716510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6717
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados