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Loss of Ifnar1 in Pancreatic Acinar Cells Ameliorates the Disease Course of Acute Pancreatitis

Type I interferon constitutes an essential component of the combinational therapy against viral disease. Acute pancreatitis is one side effect of type I interferon-based therapy, implying that activation of type I interferon signaling affects the homeostasis and integrity of pancreatic acinar cells....

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Vydáno v:PLoS One
Hlavní autoři: Miller, Katharina J., Raulefs, Susanne, Kong, Bo, Steiger, Katja, Regel, Ivonne, Gewies, Andreas, Kleeff, Jörg, Michalski, Christoph W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664425/
https://ncbi.nlm.nih.gov/pubmed/26618925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143735
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