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Aldehyde dehydrogenase 1A1 in stem cells and cancer

The human genome contains 19 putatively functional aldehyde dehydrogenase (ALDH) genes, which encode enzymes critical for detoxification of endogenous and exogenous aldehyde substrates through NAD(P)(+)-dependent oxidation. ALDH1 has three main isotypes, ALDH1A1, ALDH1A2, and ALDH1A3, and is a marke...

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Pubblicato in:Oncotarget
Autori principali: Tomita, Hiroyuki, Tanaka, Kaori, Tanaka, Takuji, Hara, Akira
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905455/
https://ncbi.nlm.nih.gov/pubmed/26783961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6920
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