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Aldehyde dehydrogenase 1A1 in stem cells and cancer

The human genome contains 19 putatively functional aldehyde dehydrogenase (ALDH) genes, which encode enzymes critical for detoxification of endogenous and exogenous aldehyde substrates through NAD(P)(+)-dependent oxidation. ALDH1 has three main isotypes, ALDH1A1, ALDH1A2, and ALDH1A3, and is a marke...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tomita, Hiroyuki, Tanaka, Kaori, Tanaka, Takuji, Hara, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905455/
https://ncbi.nlm.nih.gov/pubmed/26783961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6920
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