Targeting Aldehyde Dehydrogenase Cancer Stem Cells in Ovarian Cancer

Aldehyde dehydrogenase-1A1 (ALDH1A1) expression characterizes a subpopulation of cells with tumor initiating or cancer stem cell properties in several malignancies. Our goal was to characterize the phenotype of ALDH1A1-positive ovarian cancer cells and examine the biological effects of ALDH1A1 gene...

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Autori principali: Landen, Charles N., Goodman, Blake, Katre, Ashwini A., Steg, Adam D., Nick, Alpa M., Stone, Rebecca L., Miller, Lance D., Mejia, Pablo Vivas, Jennings, Nicolas B., Gershenson, David M., Bast, Robert C., Coleman, Robert L., Lopez-Berestein, Gabriel, Sood, Anil K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005138/
https://ncbi.nlm.nih.gov/pubmed/20889728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0563
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