Targeting Aldehyde Dehydrogenase Cancer Stem Cells in Ovarian Cancer

Aldehyde dehydrogenase-1A1 (ALDH1A1) expression characterizes a subpopulation of cells with tumor initiating or cancer stem cell properties in several malignancies. Our goal was to characterize the phenotype of ALDH1A1-positive ovarian cancer cells and examine the biological effects of ALDH1A1 gene...

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Detalhes bibliográficos
Main Authors: Landen, Charles N., Goodman, Blake, Katre, Ashwini A., Steg, Adam D., Nick, Alpa M., Stone, Rebecca L., Miller, Lance D., Mejia, Pablo Vivas, Jennings, Nicolas B., Gershenson, David M., Bast, Robert C., Coleman, Robert L., Lopez-Berestein, Gabriel, Sood, Anil K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005138/
https://ncbi.nlm.nih.gov/pubmed/20889728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0563
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