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Aldehyde dehydrogenase 1A1 in stem cells and cancer

The human genome contains 19 putatively functional aldehyde dehydrogenase (ALDH) genes, which encode enzymes critical for detoxification of endogenous and exogenous aldehyde substrates through NAD(P)(+)-dependent oxidation. ALDH1 has three main isotypes, ALDH1A1, ALDH1A2, and ALDH1A3, and is a marke...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Tomita, Hiroyuki, Tanaka, Kaori, Tanaka, Takuji, Hara, Akira
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905455/
https://ncbi.nlm.nih.gov/pubmed/26783961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6920
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