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Do changes in the c-MYC coding sequence contribute to tumorigenesis?
The role of changes in the c-MYC coding sequence in cancer is controversial. Overexpression of wild-type protein is sufficient to drive tumorigenesis, yet point mutations in c-MYC are common in Burkitt's lymphoma. Our discovery that disparate tumor-associated mutations in c-MYC have similar pro...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4904990/ https://ncbi.nlm.nih.gov/pubmed/27308414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.965631 |
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