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Rationale-based therapeutic combinations with PI3K inhibitors in cancer treatment
The PI3K/AKT/mTOR signaling is important for cell proliferation, survival, and metabolism. Hyperactivation of this pathway is one of the most common signaling abnormalities observed in cancer and a substantial effort has recently been made to develop molecules targeting this signaling cascade. Howev...
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| Publicado no: | Mol Cell Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4904898/ https://ncbi.nlm.nih.gov/pubmed/27308344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.963447 |
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