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Metabolic alterations accompanying oncogene-induced senescence

Senescence is defined as a stable cell growth arrest. Oncogene-induced senescence (OIS) occurs in normal primary human cells after activation of an oncogene in the absence of other cooperating oncogenic stimuli. OIS is therefore considered a bona fide tumor suppression mechanism in vivo. Indeed, ove...

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Bibliographic Details
Published in:Mol Cell Oncol
Main Authors: Aird, Katherine M, Zhang, Rugang
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904889/
https://ncbi.nlm.nih.gov/pubmed/27308349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.963481
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