Oncogene-induced senescence results in marked metabolic and bioenergetic alterations

Oncogene-induced senescence (OIS) is characterized by permanent growth arrest and the acquisition of a secretory, pro-inflammatory state. Increasingly, OIS is viewed as an important barrier to tumorgenesis. Surprisingly, relatively little is known about the metabolic changes that accompany and there...

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Autores principales: Quijano, Celia, Cao, Liu, Fergusson, Maria M, Romero, Hector, Liu, Jie, Gutkind, Sarah, Rovira, Ilsa I, Mohney, Robert P, Karoly, Edward D, Finkel, Toren
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350879/
https://ncbi.nlm.nih.gov/pubmed/22421146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.19800
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