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Nucleotide Metabolism, Oncogene-Induced Senescence and Cancer
Senescence is defined as a stable cell growth arrest. Oncogene-induced senescence (OIS) occurs when an activated oncogene is expressed in a normal cell. OIS acts as a bona fide tumor suppressor mechanism by driving stable growth arrest of cancer progenitor cells harboring the initial oncogenic hit....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4115046/ https://ncbi.nlm.nih.gov/pubmed/24486217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2014.01.017 |
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