Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan

Tumour blood vessels are gateways for distant metastasis. Recent studies have revealed that tumour endothelial cells (TECs) demonstrate distinct phenotypes from their normal counterparts. We have demonstrated that features of TECs are different depending on tumour malignancy, suggesting that TECs co...

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Publicado en:Sci Rep
Autores principales: Maishi, Nako, Ohba, Yusuke, Akiyama, Kosuke, Ohga, Noritaka, Hamada, Jun-ichi, Nagao-Kitamoto, Hiroko, Alam, Mohammad Towfik, Yamamoto, Kazuyuki, Kawamoto, Taisuke, Inoue, Nobuo, Taketomi, Akinobu, Shindoh, Masanobu, Hida, Yasuhiro, Hida, Kyoko
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904795/
https://ncbi.nlm.nih.gov/pubmed/27295191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28039
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