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Hypoxia-Induced Reactive Oxygen Species Cause Chromosomal Abnormalities in Endothelial Cells in the Tumor Microenvironment

There is much evidence that hypoxia in the tumor microenvironment enhances tumor progression. In an earlier study, we reported abnormal phenotypes of tumor-associated endothelial cells such as those resistant to chemotherapy and chromosomal instability. Here we investigated the role of hypoxia in th...

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Main Authors: Kondoh, Miyako, Ohga, Noritaka, Akiyama, Kosuke, Hida, Yasuhiro, Maishi, Nako, Towfik, Alam Mohammad, Inoue, Nobuo, Shindoh, Masanobu, Hida, Kyoko
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829944/
https://ncbi.nlm.nih.gov/pubmed/24260373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080349
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