ROS enhance angiogenic properties via regulation of NRF2 in tumor endothelial cells

Reactive oxygen species (ROS) are unstable molecules that activate oxidative stress. Because of the insufficient blood flow in tumors, the tumor microenvironment is often exposed to hypoxic condition and nutrient deprivation, which induces ROS accumulation. We isolated tumor endothelial cells (TECs)...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Hojo, Takayuki, Maishi, Nako, Towfik, Alam Mohammad, Akiyama, Kosuke, Ohga, Noritaka, Shindoh, Masanobu, Hida, Yasuhiro, Minowa, Kazuyuki, Fujisawa, Toshiaki, Hida, Kyoko
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542202/
https://ncbi.nlm.nih.gov/pubmed/28525375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17567
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