Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan

Tumour blood vessels are gateways for distant metastasis. Recent studies have revealed that tumour endothelial cells (TECs) demonstrate distinct phenotypes from their normal counterparts. We have demonstrated that features of TECs are different depending on tumour malignancy, suggesting that TECs co...

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izdano v:Sci Rep
Main Authors: Maishi, Nako, Ohba, Yusuke, Akiyama, Kosuke, Ohga, Noritaka, Hamada, Jun-ichi, Nagao-Kitamoto, Hiroko, Alam, Mohammad Towfik, Yamamoto, Kazuyuki, Kawamoto, Taisuke, Inoue, Nobuo, Taketomi, Akinobu, Shindoh, Masanobu, Hida, Yasuhiro, Hida, Kyoko
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904795/
https://ncbi.nlm.nih.gov/pubmed/27295191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28039
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