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Negative Allosteric Modulation of the mGluR5 Receptor Reduces Repetitive Behaviors and Rescues Social Deficits in Mouse Models of Autism

Neurodevelopmental disorders such as autism and fragile X syndrome were long thought to be medically untreatable, on the assumption that brain dysfunctions were immutably hardwired before diagnosis. Recent revelations that many cases of autism are caused by mutations in genes that control the ongoin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Silverman, Jill L., Smith, Daniel G., Sukoff Rizzo, Stacey J., Karras, Michael N., Turner, Sarah M., Tolu, Seda S., Bryce, Dianne K., Smith, Deborah L., Fonseca, Kari, Ring, Robert H., Crawley, Jacqueline N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904784/
https://ncbi.nlm.nih.gov/pubmed/22539775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003501
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