Repetitive Self-Grooming Behavior in the BTBR Mouse Model of Autism is Blocked by the mGluR5 Antagonist MPEP

Autism is a neurodevelopmental disorder characterized by abnormal reciprocal social interactions, communication deficits, and repetitive behaviors with restricted interests. BTBR T+tf/J (BTBR) is an inbred mouse strain that shows robust behavioral phenotypes with analogies to all three of the diagno...

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Main Authors: Silverman, Jill L, Tolu, Seda S, Barkan, Charlotte L, Crawley, Jacqueline N
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827881/
https://ncbi.nlm.nih.gov/pubmed/20032969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2009.201
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