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The effects of the mGluR5 antagonist MPEP and the mGluR2/3 antagonist LY341495 on rats’ performance in the 5-choice serial reaction time task.

Schizophrenia is characterized by attentional deficits possibly associated with glutamate dysfunction. The role of postsynaptic metabotropic glutamate 5 (mGluR5) or presynaptic inhibitory mGluR2/3 on attention is currently unknown. We investigated the effects of the mGluR5 antagonist MPEP and the mG...

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Autors principals: Semenova, Svetlana, Markou, Athina
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847349/
https://ncbi.nlm.nih.gov/pubmed/17126859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2006.10.003
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