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Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor
[Image: see text] Novel oxazolobenzimidazoles are described as potent and selective positive allosteric modulators of the metabotropic glutamate receptor 2. The discovery of this class and optimization of its physical and pharmacokinetic properties led to the identification of potent and orally bioa...
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Main Authors: | , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Chemical Society
2010
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007895/ https://ncbi.nlm.nih.gov/pubmed/24900224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100115a |
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