Discovery of Oxazolobenzimidazoles as Positive Allosteric Modulators for the mGluR2 Receptor

[Image: see text] Novel oxazolobenzimidazoles are described as potent and selective positive allosteric modulators of the metabotropic glutamate receptor 2. The discovery of this class and optimization of its physical and pharmacokinetic properties led to the identification of potent and orally bioa...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Principais autores: Garbaccio, Robert M., Brnardic, Edward J., Fraley, Mark E., Hartman, George D., Hutson, Pete H., O'Brien, Julie A., Magliaro, Brian C., Uslaner, Jason M., Huszar, Sarah L., Fillgrove, Kerry L., Small, James H., Tang, Cuyue, Kuo, Yuhsin, Jacobson, Marlene A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007895/
https://ncbi.nlm.nih.gov/pubmed/24900224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100115a
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados