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Deconvolution of Ensemble Chromatin Interaction Data Reveals the Latent Mixing Structures in Cell Subpopulations

Chromosome conformation capture (3C) experiments provide a window into the spatial packing of a genome in three dimensions within the cell. This structure has been shown to be correlated with gene regulation, cancer mutations, and other genomic functions. However, 3C provides mixed measurements on a...

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Bibliografiska uppgifter
I publikationen:J Comput Biol
Huvudupphovsmän: Sefer, Emre, Duggal, Geet, Kingsford, Carl
Materialtyp: Artigo
Språk:Inglês
Publicerad: Mary Ann Liebert, Inc. 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904159/
https://ncbi.nlm.nih.gov/pubmed/27267775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2015.0210
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