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Deconvolution of Ensemble Chromatin Interaction Data Reveals the Latent Mixing Structures in Cell Subpopulations

Chromosome conformation capture (3C) experiments provide a window into the spatial packing of a genome in three dimensions within the cell. This structure has been shown to be correlated with gene regulation, cancer mutations, and other genomic functions. However, 3C provides mixed measurements on a...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Sefer, Emre, Duggal, Geet, Kingsford, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904159/
https://ncbi.nlm.nih.gov/pubmed/27267775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2015.0210
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