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Deconvolution of Ensemble Chromatin Interaction Data Reveals the Latent Mixing Structures in Cell Subpopulations
Chromosome conformation capture (3C) experiments provide a window into the spatial packing of a genome in three dimensions within the cell. This structure has been shown to be correlated with gene regulation, cancer mutations, and other genomic functions. However, 3C provides mixed measurements on a...
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| Pubblicato in: | J Comput Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Mary Ann Liebert, Inc.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4904159/ https://ncbi.nlm.nih.gov/pubmed/27267775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2015.0210 |
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