Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells

High mobility group protein B1 (HMGB1) is a late inflammatory mediator that exaggerates septic symptoms. Adiponectin, an adipokine, has potent anti-inflammatory properties. However, possible effects of adiponectin on lipopolysaccharide- (LPS-) induced HMGB1 release are unknown. The aim of this study...

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Detalhes bibliográficos
Publicado no:Mediators Inflamm
Main Authors: Elfeky, Mohamed, Kaede, Ryuji, Okamatsu-Ogura, Yuko, Kimura, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904123/
https://ncbi.nlm.nih.gov/pubmed/27313399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5701959
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