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The Induction of HMGB1 Release from RAW 264.7 Cells by Transfected DNA
High mobility group protein 1 (HMGB1) is a non-histone nuclear protein that can activate innate immunity when in an extracellular location. As shown in in vitro studies, while polyinosinic-polycytidylic acid [poly (I:C)] and LPS, TLR3 and TLR4 ligands respectively, can induce HMGB1 release from macr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724460/ https://ncbi.nlm.nih.gov/pubmed/18031817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.10.019 |
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