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The Induction of HMGB1 Release from RAW 264.7 Cells by Transfected DNA

High mobility group protein 1 (HMGB1) is a non-histone nuclear protein that can activate innate immunity when in an extracellular location. As shown in in vitro studies, while polyinosinic-polycytidylic acid [poly (I:C)] and LPS, TLR3 and TLR4 ligands respectively, can induce HMGB1 release from macr...

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Bibliografische gegevens
Hoofdauteurs: Jiang, Weiwen, Pisetsky, David S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724460/
https://ncbi.nlm.nih.gov/pubmed/18031817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.10.019
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