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Colitis-induced bladder afferent neuronal activation is regulated by BDNF through PLCγ pathway

Patients with inflammatory bowel disease (IBD) or irritable bowel syndrome (IBS) often experience increased sensory responsiveness in the urinary bladder reflecting neurogenic bladder overactivity. Here we demonstrate that colitis-induced up-regulation of the phospholipase C gamma (PLCγ) pathway dow...

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Publicat a:Exp Neurol
Autors principals: Xia, Chunmei, Shen, Shanwei, Hashmi, Fiza, Qiao, Li-Ya
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4903097/
https://ncbi.nlm.nih.gov/pubmed/26687970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.12.006
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