Endogenous BDNF augments NMDA receptor phosphorylation in the spinal cord via PLCγ, PKC, and PI3K/Akt pathways during colitis

BACKGROUND: Spinal central sensitization is an important process in the generation and maintenance of visceral hypersensitivity. The release of brain-derived neurotrophic factor (BDNF) from the primary afferent neurons to the spinal cord contributes to spinal neuronal plasticity and increases neuron...

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Publicado en:J Neuroinflammation
Main Authors: Liu, Miao, Kay, Jarren C, Shen, Shanwei, Qiao, Li-Ya
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545933/
https://ncbi.nlm.nih.gov/pubmed/26289587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0371-z
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