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Endogenous PI3K/Akt and NMDAR act independently in the regulation of CREB activity in lumbosacral spinal cord in cystitis

The integral interaction of signaling components in the regulation of visceral inflammation-induced central sensitization in the spinal cord has not been well studied. Here we report that phosphoinositide 3-kinase (PI3K)-dependent Akt activation and N-Methyl-D-aspartic acid receptor (NMDAR) in lumbo...

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Bibliografiske detaljer
Main Authors: Kay, Jarren C, Xia, Chun-Mei, Liu, Miao, Shen, Shanwei, Yu, Sharon J, Chung, Chulwon, Qiao, Li-Ya
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878196/
https://ncbi.nlm.nih.gov/pubmed/24184018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.10.015
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