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Induction of TRIM22 by IFN-γ Involves JAK and PC-PLC/PKC, but Not MAPKs and pI3K/Akt/mTOR Pathways

Tripartite motif (TRIM) 22 plays an important role in interferons (IFNs)-mediated antiviral activity. We previously demonstrated that interferon regulatory factor-1 (IRF-1) played a central role in IFN-γ-induced TRIM22 expression via binding to a special cis-element named 5′ extended IFN-stimulating...

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Detalhes bibliográficos
Main Authors: Gao, Bo, Xu, Wei, Wang, Yaxin, Zhong, Linmao, Xiong, Sidong
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793658/
https://ncbi.nlm.nih.gov/pubmed/23659673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2012.0170
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