Phospholipase C gamma mediates endogenous brain-derived neurotrophic factor-regulated calcitonin gene-related peptide expression in colitis-induced visceral pain

BACKGROUND: Visceral hypersensitivity is a complex pathophysiological paradigm with unclear mechanisms. Primary afferent neuronal plasticity marked by alterations in neuroactive compounds such as calcitonin gene-related peptide is suggested to underlie the heightened sensory responses. Signal transd...

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Publicado en:Mol Pain
Autores principales: Hashmi, Fiza, Liu, Miao, Shen, Shanwei, Qiao, Li-Ya
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955977/
https://ncbi.nlm.nih.gov/pubmed/27306412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916657088
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