Cortical Gene Expression After a Conditional Knockout of 67 kDa Glutamic Acid Decarboxylase in Parvalbumin Neurons

In the cortex of subjects with schizophrenia, expression of glutamic acid decarboxylase 67 (GAD67), the enzyme primarily responsible for cortical GABA synthesis, is reduced in the subset of GABA neurons that express parvalbumin (PV). This GAD67 deficit is accompanied by lower cortical levels of othe...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Schizophr Bull
Autori principali: Georgiev, Danko, Yoshihara, Toru, Kawabata, Rika, Matsubara, Takurou, Tsubomoto, Makoto, Minabe, Yoshio, Lewis, David A., Hashimoto, Takanori
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Regular Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4903066/
https://ncbi.nlm.nih.gov/pubmed/26980143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbw022
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi