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Reduced Level of Glutamic Acid Decarboxylase-67 kDa in the Prefrontal Cortex in Major Depression

Accumulating evidence suggests dysfunction of the gamma-aminobutyric acid (GABA) system in major depressive disorder (MDD). Neuroimaging studies consistently report reductions of cortical GABA in depressed patients. Our post-mortem analyses demonstrate a reduction in the density and size of GABAergi...

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Detalhes bibliográficos
Main Authors: Karolewicz, Beata, Maciag, Dorota, O'Dwyer, Gillian, Stockmeier, Craig A., Feyissa, Anteneh M., Rajkowska, Grazyna
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857696/
https://ncbi.nlm.nih.gov/pubmed/20236554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1461145709990587
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