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Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters
Reelin and glutamic acid decarboxylase 67 (GAD(67)) expression down-regulation in GABAergic interneurons of mice exposed to protracted treatment with l-methionine (MET) is attributed to RELN and GAD(67) promoter cytosine-5-hypermethylation. This process recruits various transcription repressor prote...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1815468/ https://ncbi.nlm.nih.gov/pubmed/17360583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700529104 |
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