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Cortical Gene Expression After a Conditional Knockout of 67 kDa Glutamic Acid Decarboxylase in Parvalbumin Neurons

In the cortex of subjects with schizophrenia, expression of glutamic acid decarboxylase 67 (GAD67), the enzyme primarily responsible for cortical GABA synthesis, is reduced in the subset of GABA neurons that express parvalbumin (PV). This GAD67 deficit is accompanied by lower cortical levels of othe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Schizophr Bull
Egile Nagusiak: Georgiev, Danko, Yoshihara, Toru, Kawabata, Rika, Matsubara, Takurou, Tsubomoto, Makoto, Minabe, Yoshio, Lewis, David A., Hashimoto, Takanori
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4903066/
https://ncbi.nlm.nih.gov/pubmed/26980143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbw022
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