Clonidine inhibits anti-non-Gal IgM xenoantibody elicited in multiple pig-to-primate models

BACKGROUND: Survival of vascularized xenografts is dependent on pre-emptive inhibition of the xenoantibody response against galactosyltransferase knockout (GTKO) porcine organs. Our analysis in multiple GTKO pig-to-primate models of xenotransplantation has demonstrated that the anti-non-gal-α-1,3-ga...

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Veröffentlicht in:Xenotransplantation
Hauptverfasser: Stewart, John M., Tarantal, Alice F., Hawthorne, Wayne J., Salvaris, Evelyn J., O’Connell, Philip J., Nottle, Mark B., d’Apice, Anthony J. F., Cowan, Peter J., Kearns-Jonker, Mary
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902317/
https://ncbi.nlm.nih.gov/pubmed/26490547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12199
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