טוען...
Anti-nonGal specific combination treatment with an anti-idiotypic Ab and an inhibitory small molecule mitigates the xenoantibody response
BACKGROUND: B cell depletion significantly extends survival of α-1,3-galactosyltranferase knockout (GTKO) porcine organs in pig-to-primate models. Our previous work demonstrated that the anti-nonGal xenoantibody response is structurally restricted. Selective inhibition of xenoantigen-xenoantibody in...
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| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4056685/ https://ncbi.nlm.nih.gov/pubmed/24635144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12096 |
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