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The Anti-Non-Gal Xenoantibody Response to Xenoantigens on Gal Knockout Pig Cells is Encoded by a Restricted Number of Germline Progenitors(1)
Antibodies directed at non-gal xenoantigens are responsible for acute humoral xenograft rejection when gal knockout (GalTKO) pig organs are transplanted into non-human primates. We generated IgM and IgG gene libraries using peripheral blood lymphocytes of rhesus monkeys initiating active xenoantibod...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462011/ https://ncbi.nlm.nih.gov/pubmed/18671678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02337.x |
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