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The Anti-Non-Gal Xenoantibody Response to Xenoantigens on Gal Knockout Pig Cells is Encoded by a Restricted Number of Germline Progenitors(1)

Antibodies directed at non-gal xenoantigens are responsible for acute humoral xenograft rejection when gal knockout (GalTKO) pig organs are transplanted into non-human primates. We generated IgM and IgG gene libraries using peripheral blood lymphocytes of rhesus monkeys initiating active xenoantibod...

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Detalhes bibliográficos
Main Authors: Kiernan, Kathleen, Harnden, Ivan, Gunthart, Mirja, Gregory, Clare, Meisner, Jessica, Kearns-Jonker, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462011/
https://ncbi.nlm.nih.gov/pubmed/18671678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02337.x
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