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Rhesus monkeys and baboons develop FVIII inhibitors in response to porcine endothelial cells or islets
BACKGROUND: Xenotransplantation of porcine organs holds promise of solving the human organ donor shortage. The use of α-1,3-galactosyltransferase knockout (GTKO) pig donors mitigates hyperacute rejection, while delayed rejection is currently precipitated by potent immune and hemostatic complications...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126849/ https://ncbi.nlm.nih.gov/pubmed/24806998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12100 |
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