Epirubicin, Identified Using a Novel Luciferase Reporter Assay for Foxp3 Inhibitors, Inhibits Regulatory T Cell Activity

Forkhead box protein p3 (Foxp3) is crucial to the development and suppressor function of regulatory T cells (Tregs) that have a significant role in tumor-associated immune suppression. Development of small molecule inhibitors of Foxp3 function is therefore considered a promising strategy to enhance...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kashima, Hajime, Momose, Fumiyasu, Umehara, Hiroshi, Miyoshi, Nao, Ogo, Naohisa, Muraoka, Daisuke, Shiku, Hiroshi, Harada, Naozumi, Asai, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902191/
https://ncbi.nlm.nih.gov/pubmed/27284967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156643
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