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Activated CD8(+) T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells
Fibroblastic tumour stroma comprising mesenchymal stem cells (MSCs) and cancer-associated fibroblasts (CAFs) promotes the invasive and metastatic properties of tumour cells. Here we show that activated CD8(+) T cell-derived extracellular vesicles (EVs) interrupt fibroblastic stroma-mediated tumour p...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789986/ https://ncbi.nlm.nih.gov/pubmed/29382847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02865-1 |
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