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Preferential use of public TCR during autoimmune encephalomyelitis

How the TCR repertoire, in concert with risk-associated MHC, imposes susceptibility for autoimmune diseases is incompletely resolved. Due largely to recombinatorial biases, a small fraction of TCR α or β chains are shared by most individuals, or public. If public TCR chains modulate a TCRαβ heterodi...

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Podrobná bibliografie
Vydáno v:J Immunol
Hlavní autoři: Zhao, Yunqian, Nguyen, Phuong, Ma, Jing, Wu, Tianhua, Jones, Lindsay L., Pei, Deqing, Cheng, Cheng, Geiger, Terrence L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4902001/
https://ncbi.nlm.nih.gov/pubmed/27183575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501029
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