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Towards the total synthesis of keramaphidin B

The enantio- and diastereoselective Michael addition of a δ-valerolactone-derived pronucleophile to a substituted furanyl nitroolefin catalysed by a bifunctional cinchonine-derived thiourea has been used as the key stereocontrolling step in a new synthetic strategy to the heavily functionalised pipe...

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Bibliographic Details
Published in:Beilstein J Org Chem
Main Authors: Jakubec, Pavol, Farley, Alistair J M, Dixon, Darren J
Format: Artigo
Language:Inglês
Published: Beilstein-Institut 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901993/
https://ncbi.nlm.nih.gov/pubmed/27340496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.104
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