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Stereoselective, nitro-Mannich/lactamisation cascades for the direct synthesis of heavily decorated 5-nitropiperidin-2-ones and related heterocycles

A versatile nitro-Mannich/lactamisation cascade for the direct stereoselective synthesis of heavily decorated 5-nitropiperidin-2-ones and related heterocycles has been developed. A highly enantioenriched substituted 5-nitropiperidin-2-one was synthesised in a four component one-pot reaction combinin...

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Detalles Bibliográficos
Main Authors: Jakubec, Pavol, Cockfield, Dane M, Helliwell, Madeleine, Raftery, James, Dixon, Darren J
Formato: Artigo
Idioma:Inglês
Publicado: Beilstein-Institut 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343283/
https://ncbi.nlm.nih.gov/pubmed/22563355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.64
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