Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common and aggressive type of brain tumor. Currently, GBM has an extremely poor outcome and there is no effective treatment. In this context, genomic and transcriptomic analyses have become important tools to identify new avenues for therapies. RNA-binding...

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Vydáno v:Genome Biol
Hlavní autoři: Correa, Bruna R., de Araujo, Patricia Rosa, Qiao, Mei, Burns, Suzanne C., Chen, Chen, Schlegel, Richard, Agarwal, Seema, Galante, Pedro A. F., Penalva, Luiz O. F.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4901439/
https://ncbi.nlm.nih.gov/pubmed/27287018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0990-4
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