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Patient-derived conditionally reprogrammed cells maintain intra-tumor genetic heterogeneity
Preclinical in vitro models provide an essential tool to study cancer cell biology as well as aid in translational research, including drug target identification and drug discovery efforts. For any model to be clinically relevant, it needs to recapitulate the biology and cell heterogeneity of the pr...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5840339/ https://ncbi.nlm.nih.gov/pubmed/29511269 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22427-1 |
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