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Maintaining Tumour Heterogeneity in Patient-Derived Tumour Xenografts
Pre-clinical models often fail to capture the diverse heterogeneity of human malignancies and as such lack clinical predictive power. Patient-derived tumour xenografts (PDXs) have emerged as a powerful technology: capable of retaining the molecular heterogeneity of their originating sample. However,...
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| Publicado en: | Cancer Res |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539570/ https://ncbi.nlm.nih.gov/pubmed/26180079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0727 |
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